Image: A-dynamin-1--dynamin-3--and-clathrin-independent-pathway-of-synaptic-vesicle-recycling-mediated-by-elife01621f013

Description: At left is CME. At right is bulk endocytosis followed by fragmentation of bulk endosomes to generate new vesicles. As membranes of bulk endosomes are expected to be enriched in SV proteins, functional SVs may be generated by this mechanism. The uncoated invaginations occurring near active zones and described by Watanabe et al. (2013a and 2013b) may represent a form of this type of clathrin-independent endocytosis. At subsequent exo–endocytic cycles, however, CME may help reestablish SV reformation with high fidelitiy.
Title: A-dynamin-1--dynamin-3--and-clathrin-independent-pathway-of-synaptic-vesicle-recycling-mediated-by-elife01621f013
Credit: Image file from Wu Y, O'Toole E, Girard M, Ritter B, Messa M, Liu X, McPherson P, Ferguson S, De Camilli P (2014). "A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis". eLife. DOI:10.7554/eLife.01621. PMID 24963135. PMC: 4107917.
Author: Wu Y, O'Toole E, Girard M, Ritter B, Messa M, Liu X, McPherson P, Ferguson S, De Camilli P
Permission: .mw-parser-output .responsive-license-cc{clear:both;text-align:center;box-sizing:border-box;width:100%;justify-content:space-around;align-items:center;margin:0.5em auto;background-color:#f9f9f9;border:2px solid #e0e0e0;border-spacing:8px;display:flex}.mw-parser-output .responsive-license-cc div{margin:4px}.mw-parser-output .rlicense-text div{margin:0.5em auto}@media screen and (max-width:640px){.mw-parser-output .responsive-license-cc{flex-flow:column}.mw-parser-output .rlicense-text{order:1}} This file is licensed under the Creative Commons Attribution 4.0 International license. You are free: to share – to copy, distribute and transmit the work to remix – to adapt the work Under the following conditions: attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. https://creativecommons.org/licenses/by/4.0CC BY 4.0 Creative Commons Attribution 4.0 truetrue
Usage Terms: Creative Commons Attribution 4.0
License: CC BY 4.0
License Link: https://creativecommons.org/licenses/by/4.0
Attribution Required?: Yes